Endoaxis Formula 6 (Decrease DHT Conversion)

Herbs and minerals to support a decreased 5a-reductase response.

Testosterone is a crucial hormone for skeletal muscle performance, brain health, bone matrix activity, sexual performance and responsiveness, and longevity support. 5a-DHT is the potent, 5a-reductase-dependent metabolite of testosterone, considered 4x per potent than testosterone itself (although also very short-lived in circulation).

Problems can arise when testosterone is metabolized more readily into 5a-DHT over the 5b-reductase pathway. Although both men and women can benefit from 5a-DHT, it needs to be
in healthy balance and alignment with their metabolic needs.

FORMULA ANALYSIS
Keep in mind, conditions like PCOS and genetics can play a strong role in 5a-reductase preference as well. But when 5a-reductase is high, if the patient struggles with symptoms
such as diffuse hair thinning for women or the classic “male pattern baldness” in men, painful cystic acne, or excess facial and body hair growth, there may be a need to reduce the 5a-reductase activity through targeted herbs and minerals, while also digging deeper to support any underlying stress or blood sugar imbalance. Our formula uniquely targets 5a-reductase activity by utilizing 5a-reductase-inhibiting herbs, as well as herbs that reduce inflammation and help to gently regulate insulin response in the body, including:

Saw Palmetto
Saw palmetto (Serenoa repens) has been investigated for its potential to reduce the activity of the enzyme 5α-reductase, which plays a crucial role in the conversion of testosterone to dihydrotestosterone (DHT). Several studies have suggested that saw palmetto extract may inhibit the activity of 5 α-reductase via its active constituents, including lauric acid, b-sitosterol, stigmasterol, lupenone and cycloartenol[1], thereby supporting and potentially alleviating the symptoms of DHT-associated conditions including benign prostatic hypertrophy in men (BPH) and androgenic alopecia in both
men and women[2][3]

Nettle Root
Nettle Root (Urtica dioica) contains phytochemicals that reduce the activity of 5a-reductase within the cytoplasm of our cells. In addition, nettle root uniquely (not the leaf) contains beta-sitosterol that inhibits the binding of DHT to receptor sites
in the skin, hair and prostate[4] [5].

Curcumin
Curcumin (curcuma longa), exhibits anti-inflammatory and antioxidant effects which support not only the tissues being impacted by DHT, but also reduce the pro-inflammatory response that can trigger the up-regulation of 5a-reductase
enzymatic activity[6][7].

Zinc
Zinc is an essential mineral that supports reproductive health and hormone balance. Studies have demonstrated that among many of its attributes, zinc can help reduce 5a-reductase response within our tissues.

SUGGESTED USE: Take 1 capsule 3 times a day with a meal or as directed by
your healthcare practitioner.

CAUTION: Do not use if pregnant or nursing. Consult your physician before use if you have a medical condition, or taking any medication. Do not use product if the safety seal is broken or damaged. Keep out of reach of children.

MADE WITHOUT: Corn, soy, or wheat.

The information on this website is provided for educational purposes only and is not intended to replace advice from your physician or healthcare provider. These statements have not been evaluated by the Food and Drug Administration. Products sold on this site are not intended to diagnose, treat, cure, or prevent any disease.